On an isolated island in the South Pacific, there is an outbreak in a top-secret military facility where Colonel Aiden Wexler is researching biological weapons. Ten years later, a small squad is sent to the island to investigate the status of the facility. They shall contact their helicopter a couple of hours later; otherwise the place will be bombed and totally destroyed. Along their journey, they are attacked by zombies and when they reach the building, they find Aiden alive. Out of the blue, Dr. Mikaela Usylvich that is assisting the mission discloses that is Aiden's daughter.